Systematic and general method for quantifying localization in microscopy images
Sheng, H., Stauffer, W., & Lim, H. N. (2016). "Systematic and general method for quantifying localization in microscopy images." Biology open, 5(12), 1882-1893.
CV
Education
- Ph.D in Integrative Biology, University of California at Berkeley, 2019
- B.S. in Biological Sciences, Peking University, 2014
Work experience
- Feburary, 2020-Present: Senior Data Scientist, Bioinformatics
- Roche Sequencing Solutions, Inc. Santa Clara, CA
- Working on primary bioinformatics data analysis of nanopore sequencing
- August, 2019-January, 2020: Post-Doctoral Researcher
- University of California, Berkeley
- Study the change in variance of gene expression during aging
- August, 2014-May, 2019: Graduate Student Instructor
- University of California, Berkeley
- Courses Taught: Bio 1B (General Biology), IB 115 (Introduction to Systems Biology and Medicine)
- Bio 1B is a general introduction to organismal diversity, ecology, and evolutionary biology. It is intended for students majoring in the biological sciences, but it is open to all qualified students.
- IB 115 is an introductory course to system biology and mathematical models. It mainly focuses on bacterial systems but also generalize to infectious diseases and medicical research.
Skills
- Programming Skills
- C/C++
- Java
- Python
- R
- Matlab
- Mathematica
- Bash
- ImageJ Macro
- Experimental Skills
- Molecular Biology/Cloning
- Fluorescence Microscopy
- Bacteria/Yeast Cell Culture
- Other Skills
- Latex
- Excel
Publications
Nucleoid and cytoplasmic localization of small RNAs in Escherichia coli
Sheng, H., Stauffer, W. T., Hussein, R., Lin, C., & Lim, H. N. (2017). "Nucleoid and cytoplasmic localization of small RNAs in Escherichia coli." Nucleic acids research, 45(5), 2919-2934.
EzColocalization: An ImageJ plugin for visualizing and measuring colocalization in cells and organisms
Stauffer, W., Sheng, H., & Lim, H. N. (2018). "EzColocalization: An ImageJ plugin for visualizing and measuring colocalization in cells and organisms." Scientific reports, 8(1), 15764.
Blood-brain barrier dysfunction in aging induces hyper-activation of TGF-beta signaling and chronic yet reversible neural dysfunction
Senatorov, V. V., Friedman, A. R., Milikovsky, D. Z., Ofer, J., Saar-Ashkenazy, R., Charbash, A., ... H. Sheng, ... & Ramsay, H. J. (2016). "Systematic and general method for quantifying localization in microscopy images." bioRxiv, 537431.
Object Recognition at Higher Regions of the Ventral Visual Stream via Dynamic Inference
Sorooshyari, S. K., Sheng, H., & Poor, H. V. (2020). Object Recognition at Higher Regions of the Ventral Visual Stream via Dynamic Inference. Frontiers in computational neuroscience, 14, 46.